Education:
PhD. Biomedical engineering, Northwestern University
Interests:
Arterial spin labeling, fMRI, pharmacological MRI
Projects:
Publications:
1: Detre JA, Rao H, Wang DJ, Chen YF, Wang Z. Applications of arterial spin labeled MRI in the brain. J Magn Reson Imaging. 2012 Jan 13. doi: 10.1002/jmri.23581. [Epub ahead of print] PubMed PMID: 22246782.
2: Musiek ES, Chen Y, Korczykowski M, Saboury B, Martinez PM, Reddin JS, Alavi A, Kimberg DY, Wolk DA, Julin P, Newberg AB, Arnold SE, Detre JA. Direct comparison of fluorodeoxyglucose positron emission tomography and arterial spin labeling magnetic resonance imaging in Alzheimer’s disease. Alzheimers Dement. 2012 Jan;8(1):51-9. Epub 2011 Oct 21. PubMed PMID: 22018493.
3: Chen Y, Wolk DA, Reddin JS, Korczykowski M, Martinez PM, Musiek ES, Newberg AB, Julin P, Arnold SE, Greenberg JH, Detre JA. Voxel-level comparison of arterial spin-labeled perfusion MRI and FDG-PET in Alzheimer disease. Neurology. 2011 Nov 29;77(22):1977-85. Epub 2011 Nov 16. PubMed PMID: 22094481.
4: Chen Y, Wang DJ, Detre JA. Comparison of arterial transit times estimated using arterial spin labeling. MAGMA. 2011 Aug 24. [Epub ahead of print] PubMed PMID: 21863374.
5: Wang DJ, Chen Y, Fernández-Seara MA, Detre JA. Potentials and challenges for arterial spin labeling in pharmacological magnetic resonance imaging. J Pharmacol Exp Ther. 2011 May;337(2):359-66. Epub 2011 Feb 11. PubMed PMID: 21317356.
6: Chen Y, Wang DJ, Detre JA. Test-retest reliability of arterial spin labeling with common labeling strategies. J Magn Reson Imaging. 2011 Apr;33(4):940-9. doi: 10.1002/jmri.22345. PubMed PMID: 21448961.
7: Chen Y, Wan HI, O’Reardon JP, Wang DJ, Wang Z, Korczykowski M, Detre JA. Quantification of cerebral blood flow as biomarker of drug effect: arterial spin labeling phMRI after a single dose of oral citalopram. Clin Pharmacol Ther. 2011 Feb;89(2):251-8. Epub 2010 Dec 29. PubMed PMID: 21191380.
8: Chen Y, Parrish TB. Caffeine dose effect on activation-induced BOLD and CBF responses. Neuroimage. 2009 Jul 1;46(3):577-83. Epub 2009 Mar 13. PubMed PMID: 19289172.
9: Chen Y, Parrish TB. Caffeine’s effects on cerebrovascular reactivity and coupling between cerebral blood flow and oxygen metabolism. Neuroimage. 2009 Feb 1;44(3):647-52. Epub 2008 Oct 19. PubMed PMID: 19000770.
10: Shin W, Horowitz S, Ragin A, Chen Y, Walker M, Carroll TJ. Quantitative cerebral perfusion using dynamic susceptibility contrast MRI: evaluation of reproducibility and age- and gender-dependence with fully automatic image postprocessing algorithm. Magn Reson Med. 2007 Dec;58(6):1232-41. PubMed PMID: 17969025.